Revista del Nacional (Itauguá) https://revistadelnacional.com.py/index.php/inicio <p>The Revista del Nacional (Itauguá) (ISSN 2307-3640 online version) is the official organ of scientific dissemination of the National Medical Center - National Hospital, Itauguá-Paraguay under the Ministry of Public Health and Social Welfare.</p> <p>The objective of this journal is to publish with standards of excellence, the investigative, scientific and intellectual production of original and unpublished works, of current topics (studies that do not exceed two years before publication), generated by national and international professionals in the area of ​​clinical medicine, biomedical research (application of biology and physiology to medicine), dentistry, nursing, nutrition, public health, microbiology, molecular biology, health biotechnology, and other areas related to health. The manuscripts of traditional, complementary and integrative medicines will be exhaustively evaluated by the editorial board for their acceptance, having as main criteria the relevance and interest of the community. </p> <p style="background: white;">Since <strong>volume 17, year 2025</strong>, the <strong>Revista del Nacional (Itauguá)</strong> adopts an annual periodicity in the form of <strong>continuous publication (CP</strong>), allowing the progressive incorporation of new content throughout the year.</p> <p><strong>Revista del Nacional (Itauguá)</strong> does not charge fees for evaluation or publication, it is freely accessible and free of charge.</p> es-ES revdelnacionalhn@gmail.com (Lic. Gloria Guerreño) revdelnacionalhn@gmail.com (Lic. Gloria Guerreño) Fri, 07 Mar 2025 00:00:00 -0600 OJS 3.3.0.6 http://blogs.law.harvard.edu/tech/rss 60 Maternal anxiety and depression and its impact on breastfeeding self-efficacy https://revistadelnacional.com.py/index.php/inicio/article/view/229 <p><strong>Introduction:</strong> breastfeeding self-efficacy is a crucial factor influencing success and duration. Studies have shown that maternal anxiety and depression can negatively affect breastfeeding self-efficacy, which may hinder continuation of breastfeeding. Understanding this relationship is essential in designing interventions to improve maternal well-being and breastfeeding practices.<br><strong>Objective:</strong> this study aimed to explore the relationship between maternal anxiety and depression and breastfeeding self-efficacy, and to describe the sociodemographic and mental health characteristics of the participants.<br><strong>Methodology:</strong> this was an observational descriptive study with a cross-sectional design was conducted on 108 breastfeeding women in Paraguay. A non-probabilistic convenience sampling method was used. Participants completed the Generalized Anxiety Disorder-7 (GAD-7), Edinburgh Postnatal Depression Scale (EPDS), and Breastfeeding Self-Efficacy Scale-Short Form (BSES-SF). Data were analyzed using SPSS, and the Mann-Whitney U test was used to determine the associations between anxiety, depression, and self-efficacy.<br><strong>Results:</strong> a total of 30.6 % of the participants reported anxiety, and 48.1% showed signs of postpartum depression. Women with anxiety and depression had significantly lower breastfeeding self-efficacy scores (p=0.044 and p=0.048, respectively).<br><strong>Conclusion:</strong> these results suggest that maternal anxiety and depression negatively affect<br>breastfeeding self-efficacy. Addressing mental health issues in breastfeeding mothers is essential to improving self-efficacy and, consequently, breastfeeding outcomes.</p> Julio Torales, Amín González-Ríos, Marcelo O’Higgins, Tomás Caycho-Rodríguez, Antonio Ventriglio, João Mauricio Castaldelli-Maia, Iván Barrios Copyright (c) 2024 Julio Torales, Amín González-Ríos, Marcelo O’Higgins, Tomás Caycho-Rodríguez, Antonio Ventriglio, João Mauricio Castaldelli-Maia, Iván Barrios https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/229 Mon, 30 Dec 2024 00:00:00 -0600 Obstetric and perinatal characteristics in patients with birth canal tears https://revistadelnacional.com.py/index.php/inicio/article/view/230 <p><strong>Introduction:</strong> birth canal tears are undesirable complications that occur during vaginal delivery, causing aesthetic and functional problems in the perineum or in the birth canal itself. Its prevalence, far from decreasing with current knowledge of obstetric medicine, has been gradually increasing in recent years.<br><strong>Objective:</strong> to determine the obstetric and perinatal characteristics in patients with birth canal tears treated at the Centro Médico Nacional– Hospital Nacional in the period of 2021-2022.<br><strong>Methodology:</strong> this was an observational, descriptive, cross-sectional, and retrospective study, including women with birth canal injuries treated at the Centro Médico Nacional– Hospital Nacional in the period 2021-2022.Descriptive statistics were used for the data analysis.<br><strong>Results:</strong> 198 women with birth canal injuries were identified. The most frequent age range was 19- 29 years and most of them lived in the Central department. Most of the birth canal tears were observed innulliparous women (47.5 %) and without a previous cesarean section (92.9 %); the most frequent injury was the cervical tear (64.1 %). The most common morbidity was uterine atony (20.7 %). Regarding perinatal data, normal weight and term gestational age were more frequent.<br><strong>Conclusion:</strong> cervical tears were the most frequent birth canal injury in nulliparous women without previous cesarean section with an age range of 19-29 years and from the Central department.</p> Karen Leticia Brítez Ramirez, Sandra Godoy López, María Raquel Segovia de Vázquez Copyright (c) 2024 Karen Leticia Brítez Ramirez, Sandra Godoy López, María Raquel Segovia de Vázquez https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/230 Mon, 30 Dec 2024 00:00:00 -0600 Psychometric evidence of the Impact of Events Scale (IES-6) in Peruvian adolescents https://revistadelnacional.com.py/index.php/inicio/article/view/231 <p><strong>Introduction:</strong> symptoms of Post Traumatic Stress Disorder (PTSD) are a frequent public health problem in adolescent population. Empirical evidence shows that adverse events during adolescence can affect early adulthood and predict various psychological problems. Ongoing assessment of PTSD is essential for prevention and the availability of reliable, evidence-based psychological instruments is necessary.<br><strong>Objective:</strong> to analyze the psychometric properties of the Impact of Events Scale-6 (IES-6) in the general adolescent population.<br><strong>Methodology:</strong> we used an instrumental research, quantitative and cross-sectional approach. A total of 2877 adolescents from Huancavelica participated, who answered the IES-6 and other psychological instruments. Statistical analyses were performed with structural equation modeling and item response theory.<br><strong>Results:</strong> the IES-6 presents adequate evidence of content validity, unidimensional structure, reliability, measurement invariance according to sex and relationship with suicidal ideation, generalized anxiety and depression. Items 5 and 3 presented the highest discrimination and information, and the scale is accurate for high levels of PTSD.<br><strong>Conclusion:</strong> the IES-6 presents adequate sources of validity evidence and is a useful instrument for the assessment of PTSD symptoms in Peruvian adolescents. Its use is recommended in research and prevention and follow-up programs in public health and education.</p> Jonatan Baños-Chaparro, Paul Ynquillay-Lima, Tomás Caycho-Rodríguez Copyright (c) 2024 Jonatan Baños-Chaparro https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/231 Mon, 30 Dec 2024 00:00:00 -0600 Work stress and musculoskeletal symptoms in employees of a private company in the city of Asunción, Paraguay, 2023 https://revistadelnacional.com.py/index.php/inicio/article/view/232 <p><strong>Introduction:</strong> musculoskeletal disorders and work stress affect the quality of life of an organization's workers.<br><strong>Objective:</strong> to describe the level of work stress and the degree of perception of musculoskeletal symptoms in employees of a private company in the city of Asunción.<br><strong>Methodology:</strong> this was a descriptive, quantitative, observational and cross-sectional study. We used non-probabilistic convenience sampling. 45 administrative collaborators from a private company participated. The instruments used were: ILO-WHO Work Stress Scale and the Kuorinka Nordic Musculoskeletal Symptoms Questionnaire. The study variables were stress levels and musculoskeletal symptoms. MS-Excel 2016 software was used for data processing.<br><strong>Results:</strong> of a sample of 45 people, 87 % (n = 39) reported a low level of stress. On the other hand, 96 % (n = 43) presented a perception of musculoskeletal symptoms.<br><strong>Conclusion:</strong> the majority of employees reported a low level of stress. On the other hand, almost the entire sample perceived symptoms of musculoskeletal pain, located mainly in the lower back area. The relationship between the level of stress and the perception of musculoskeletal symptoms is a topic that requires more in-depth research to determine more precisely the effects of work stress on the human body. Kinesiology and Physiotherapy is a valid path for implementing plans for the prevention and treatment of musculoskeletal ailments in the context of organizations.</p> Pablo Andrés Barboza Compte, Lelis Morales-Clemotte Copyright (c) 2024 Pablo Andrés Barboza Compte, Lelis Morales-Clemotte https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/232 Mon, 30 Dec 2024 00:00:00 -0600 Training a neural network for estimating the homeostatic model of insulin resistance https://revistadelnacional.com.py/index.php/inicio/article/view/233 <p><strong>Introduction:</strong> the evaluation of the homeostatic model is a test very close to the gold standard (euglycemic clamp).<br><strong>Objective:</strong> train a multilayer perceptron-type neural network to determine the homeostatic model of insulin resistance.<br><strong>Methodology:</strong> analytical and cross-sectional study. The learning of the neural network was carried out from a database of 2004 Venezuelan adults. Subsequently, 4,363 Mexican adults were added to the database of the National Health and Nutrition Survey (ENSANUT). The variables were homeostatic model of insulin resistance (HOMA2-IR), basal insulin, and basal glucose. Multilayer perceptron-type neural networks were used.<br>Results: the training of the neural network model had a relative error of 0.003, while in the test it was 0.005. For qualitative HOMA2-IR, the percentage of incorrect predictions was 0.60 % in training, and 0.70 % in testing. After learning the model, insulin and basal glucose values from 4363 Mexican adults were added, observing that the HOMA2-IR values generated by multilayer perceptron maintained the efficiency of the model, obtaining a coefficient of determination R2 of 0.983, which implies that 98 % of the variation in HOMA2-IR values can be explained by HOMA2-IR values obtained using multilayer perceptron.<br><strong>Conclusions:</strong> the multilayer perceptron-type neural network gives results virtually identical to those obtained using the HOMA2-IR calculator. The implementation of this algorithm can be beneficial as a tool that is easy to implement in primary and specialized care systems and in hospital environments.</p> Alberto Guevara Tirado Copyright (c) 2024 Alberto Guevara Tirado https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/233 Mon, 30 Dec 2024 00:00:00 -0600 Phenotypic and genotypic characterization of carbapenemases produced by Gram-negative bacterial pathogens isolated in hospitals in Paraguay https://revistadelnacional.com.py/index.php/inicio/article/view/246 <p><strong>Introduction:</strong> the dissemination of Gram-negative bacteria resistant to carbapenems represents an important cause of morbidity and mortality, being a growing threat to public health and of great concern worldwide. Although resistance to carbapenems can be due to several mechanisms, the most relevant, clinically and epidemiologically, is enzyme production. The goals of this study were to phenotypically and genotypically characterize carbapenemases produced by clinically important Gram-negative bacilli (GNB) isolated in hospitals in Paraguay in 2022 and evaluate the susceptibility to colistin.<br><strong>Methodology:</strong> retrospective study, carried out on 1,226 GNB strains sent to the Central Laboratory during 2022 for phenotypic and genotypic characterization. Identification studies were performed out by conventional methods, susceptibility to colistin by microdilution in broth, and molecular studies for the confirmation of resistance genes.<br><strong>Results:</strong> in total, of 1226 GNB isolates, 629 (51 %) were confirmed as non-carbohydrate-fermenting GNB (89 % Acinetobacter spp.) and 597 (49 %) as carbohydrate-fermenting GNB (74 % Klebsiella pneumoniae). Carbapenemases OXA-23 (94.9 %), NDM (3.1 %), OXA-23+NDM (1.8 %) and OXA-23+NDM+OXA-58 (0.2 %) were confirmed in Acinetobacter baumannii; in K. pneumoniae: NDM (84.5 %), KPC (11.7 %), KPC+NDM (3.7 %) and NDM+OXA-48like (0.2 %); and in P. aeruginosa the prevalent was NDM (50.9 %). Colistin-associated resistance was found mainly in K. pneumoniae (24%).<br><strong>Conclusions:</strong> in our country the circulation of carbapenemase-producing bacteria is endemic. The co-production of these enzymes is confirmed. NDM is prevalent in Enterobacterales and P. aeruginosa, and OXA-23 in A. baumannii. The high resistance associated with colistin in K. pneumoniae makes it imperative to have new, more effective antimicrobials for the treatment of infections.</p> <p>&nbsp;</p> Nancy Lorena Melgarejo Touchet, Mario Fabián Martínez Mora, Cristina M Brítez, Pamela Dunjo, Aníbal Kawabata, Marcela Laconich, Juan Domingo Irala, Gloria Elizabeth Gómez Duarte, Ana María Cuevas Gorostiaga, Marta González, Evelyn López, Karina Abreu, Raquel Blasco Gavilán, Rosa Estela Portillo de Naleiro, Carolina Viera, Karen Antonella Jara Amarilla, Dolly Velázquez Sánchez, Jazmín Clarissa Pereira Martínez, Sara Ramírez, Viviana Rojas, Rocío Alejandra Lesme, Sonia Abente, Stefan Goertzen, Sofia Busignani Copyright (c) 2025 Nancy Lorena Melgarejo Touchet, Mario Fabián Martínez Mora, Cristina M Brítez, Pamela Dunjo, Aníbal Kawabata, Marcela Laconich, Juan Domingo Irala, Gloria Elizabeth Gómez Duarte, Ana María Cuevas Gorostiaga, Marta González, Evelyn López, Karina Abreu, Raquel Blasco Gavilán, Rosa Estela Portillo de Naleiro, Carolina Viera, Karen Antonella Jara Amarilla, Dolly Velázquez Sánchez, Jazmín Clarissa Pereira Martínez, Sara Ramírez, Viviana Rojas, Rocío Alejandra Lesme, Sonia Abente, Stefan Goertzen, Sofia Busignani https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/246 Fri, 07 Mar 2025 00:00:00 -0600 Neurophobia in Medical Students from Paraguay https://revistadelnacional.com.py/index.php/inicio/article/view/247 <p><strong>Introduction:</strong> neurophobia, defined as the fear or aversion to neurology due to its perceived complexity, poses a challenge in medical education. This study examines the prevalence and associated factors of neurophobia among medical students in Paraguay.<br>Objective: to explore perceptions, attitudes, and factors associated with neurophobia among medical students and identify educational strategies to enhance neurology teaching.<br><strong>Methodology:</strong> this was an observational, descriptive, and cross-sectional study conducted with a sample of 413 medical students from various Paraguayan universities. Data on sociodemographic characteristics, prior experiences in neurology, and knowledge perceptions were collected using a validated questionnaire. Descriptive and inferential statistical analyses were performed.<br><strong>Results:</strong> a total of 41.6 % of students reported a low likelihood of choosing neurology as a specialty, while 33.9 % expressed intermediate levels of fear toward this discipline. The main causes of neurophobia were theoretical teaching approaches (32.9 %) and the perceived difficulty of neuroanatomy (35.8 %). Additionally, 69.2 % considered neurology teaching to be insufficient, and 81.1 % reported a lack of extracurricular activities related to neurology.<br><strong>Conclusions:</strong> the findings highlight the need for a more practical and interactive curriculum, emphasizing clinical simulations and extracurricular activities to foster interest and confidence in neurology. These changes could mitigate neurophobia and encourage professional development in this specialty.</p> Elías René Rolón Méndez, Martín Sánchez García de Zúñiga, José Rosa Aguirre Silvero, Adriana Isabel Salinas Aquino, Marcelo Luis Iván Sarabia Guerrero, Gustavo Nabil Céspedes Añazco, Fernando Rubén Leiva Espínola, Álvaro Aguayo Centurión, Marcelo O’Higgins, Tomás Caycho-Rodríguez, Antonio Ventriglio, João Mauricio Castaldelli-Maia, Anthon Daniel Torres-Romero, Iván Barrios, Julio Torales Copyright (c) 2025 Elías René Rolón Méndez, Martín Sánchez García de Zúñiga, José Rosa Aguirre Silvero, Adriana Isabel Salinas Aquino, Marcelo Luis Iván Sarabia Guerrero, Gustavo Nabil Céspedes Añazco, Fernando Rubén Leiva Espínola, Álvaro Aguayo Centurión, Marcelo O’Higgins, Tomás Caycho-Rodríguez, Antonio Ventriglio, João Mauricio Castaldelli-Maia, Anthon Daniel Torres-Romero, Iván Barrios, Julio Torales https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/247 Fri, 07 Mar 2025 00:00:00 -0600 Characteristics of maternal mortality in Paraguay https://revistadelnacional.com.py/index.php/inicio/article/view/254 <p><strong>Introduction:</strong> maternal mortality (MM) is a critical public health indicator, especially in low- and middle-income countries. In Paraguay, although progress was made in reducing MM between 2008 and 2018, the COVID-19 pandemic reversed many of these gains. This study examines the characteristics of MM in Paraguay between 2014 and 2021.<br><strong>Objectives:</strong> to describe the sociodemographic and clinical characteristics of maternal mortality in Paraguay during the period 2014-2021.<br><strong>Methodology:</strong> a retrospective cross-sectional descriptive study was conducted using data from death certificates of the General Directorate of Strategic Health Information (DIGIES) of the Ministry of Public Health and Social Welfare. We analyzed 740 cases of maternal deaths registered in the 18 Health Regions of the country, considering sociodemographic variables and variables<br>related to causes of death.<br><strong>Results:</strong> there were 740 maternal deaths, with an average ratio of 83.91 per 100,000 live births. 2021 had the highest ratio (159.98). The majority occurred in young (58.65 %) and adult women (66.31 %), with predominant causes being diseases of Respiratory System 18.11 %, toxemia 15.81 %, and hemorrhaged 12.03 %.<br><strong>Conclusion:</strong> MM presented an increase after the COVID 19 pandemic, so the study highlights the urgent need to strengthen access to quality prenatal and obstetric care, especially in public institutions, and to address the socioeconomic inequalities that affect maternal health.</p> Miriam Espínola-Canata, Gladys Ester Mora Escobar, Carina Velázquez, Miuriel Díaz de Vivar, Marlene Chávez, Cira Bernal, Juan Edgar Tullo Gómez, Pasionaria Rosa Ramos Ruiz Díaz Copyright (c) 2025 Miriam Espínola-Canata, Gladys Ester Mora Escobar, Carina Velázquez, Miuriel Díaz de Vivar, Marlene Chávez, Cira Bernal, Juan Edgar Tullo Gómez, Pasionaria Rosa Ramos Ruiz Díaz https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/254 Sat, 22 Mar 2025 00:00:00 -0500 Gestational trophoblastic disease https://revistadelnacional.com.py/index.php/inicio/article/view/234 <p>Placental tissue proliferation gives rise to a set of related diseases, all of which are included in the term gestational trophoblastic disease (GTD). Lesions include:hydatidiform mole (complete and partial), invasive mole, choriocarcinoma, trophoblastic tumor of the placental site, and epithelioid trophoblastic tumor. This report describes a case of invasive mole diagnosed after a manual endouterine aspiration procedure, which was detected by increasing serum levels of quantitative BCHG in its controls. <br />Therefore, the importance of follow-up with serial controls of quantitative BCHG blood is demonstrated, for an opportune diagnosis and treatment.</p> María Magdalena Prieto Agüero, Karen Leticia Britez Ramírez Copyright (c) 2024 María Magdalena Prieto Agüero, Karen Leticia Britez Ramírez https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/234 Mon, 30 Dec 2024 00:00:00 -0600 Mental health in Kinesiology and Physiotherapy Undergraduate Students at the Universidad Nacional de Asunción https://revistadelnacional.com.py/index.php/inicio/article/view/235 <p>Today's digital environment has transformed the way young people interact and perceive reality. The excessive use of social networks, the phenomenon of “doomscrolling” and information overload have increased anxiety levels in 60% of post-pandemic youth, this scenario suggests that college students are particularly exposed to these stressors, which could influence their academic performance and overall well-being.</p> Mery Leonardo Aiquipa Copyright (c) 2024 Mery Leonardo Aiquipa https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/235 Mon, 30 Dec 2024 00:00:00 -0600 Reality of the Human Immunodeficiency Virus https://revistadelnacional.com.py/index.php/inicio/article/view/236 <p>Currently, the Human Immunodeficiency Virus (HIV) continues to be one of the public health problems; according to the World Health Organization (WHO), in the last year it has claimed the lives of 32.9 to 51.3 million people with an average of 40.4 million lives worldwide. It is estimated that by 2025, 95% of people with HIV should have been diagnosed, 95% should be on retroviral treatment and 95% should be able to suppress their viral load.</p> <p>&nbsp;</p> Violeta Susana Herrera Olortiga, Nito Sebastian Robles Cabanillas, Nayely Nadyely Salazar Rojas Copyright (c) 2024 Violeta Susana Herrera Olortiga, Nito Sebastian Robles Cabanillas, Nayely Nadyely Salazar Rojas https://creativecommons.org/licenses/by/4.0 https://revistadelnacional.com.py/index.php/inicio/article/view/236 Mon, 30 Dec 2024 00:00:00 -0600