Precipiting causes of acute hyperglycemic crisis in patients in the Centro Médico Nacional - Hospital Nacional
Main Article Content
Abstract
Introduction: hyperglycemic crises are the most frequent endocrinological emergencies in clinical practice and, along with hypoglycemia, are described as serious acute metabolic complications in diabetic patients.
Objective: to identify the precipiting causes of acute hyperglycemic crisis in hospitalized patients in the Centro Médico Nacional - Hospital National.
Methodology: this was an observational, descriptive, cross -sectional study of patients hospitalized at the Centro Médico Nacional - Hospital National, from May 2021 to October 2023. The data were obtained from a review of the clinical records.
Results: Of the 100 patients evaluated, the most frequent acute hyperglycemic crisis was diabetic ketoacidosis (CAD) 53 %, followed by the hyperglycemic hyperosmolar state (EHH) 25 % and the mixed state 22 %. The most frequent triggers were the abandonment of treatment, disease debut and infections. Global mortality was 12 %.
Conclusion: the most frequent causes of decompensations were abandoning treatment, novo diabetes and infectious processes.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
Mediavilla Bravo JJ. Complicaciones de la diabetes mellitus: diagnóstico y tratamiento. SEMERGEN. 2001; 27(3): 132-145.
Capel I, Berges-Raso I. Complicaciones agudas hiperglucémicas e hipoglucémicas. Medicine. 2016;12(18): 1035-42.
Aldhaeefi M, Aldardeer NF, Alkhani N, Mohammed Alqarni Sh, Alhammad AM, Alshaya AI. Updates in the management of hyperglycemic crisis. Front Clin Diabetes Healthc. 2022;2:820728.
Builes-Montaño CE, Chavarriaga A, Ballesteros L, Muñoz M, Medina S, Donado-Gomez JH, et al. Characteristics of hyperglycemic crises in an adult population in a teaching hospital in Colombia. J Diabetes Metab Disord. 2018;17(2): 143–148. doi: 10.1007/s40200-018-0353-7.
Pasquel FJ, Tsegka K, Wang H, Cardona S, Galindo RJ, Fayfman M, et al. Clinical outcomes in patients with isolated or combined diabetic ketoacidosis and hyperosmolar hyperglycemic state: a retrospective, Hospital-Based Cohort Study. Diabetes Care. 2020;43(2): 349–357. doi: 10.2337/dc19-1168.
Alourfi Z, Homsi H. Precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at auniversity hospital in Damascus. Avicenna J Med. 2015;5(1):11-5. doi: 10.4103/2231-0770.148503.
Ahuja W, Kumar N, Kumar S, Rizwan A. Precipitating risk factors, clinical presentation, and outcome of diabetic ketoacidosis in patients with type 1 diabetes. Cureus. 2019;11(5):e4789. doi: 10.7759/cureus.4789
Charoenpiriya A, Chailurkit L, Ongphiphadhanakul B. Comparisons of biochemical parameters and diabetic ketoacidosis severity in adult patients with type 1 and type 2 diabetes. BMC Endocr Disord. 2022;22(1):7. doi:10.1186/s12902-021-00922-3.
Sierra-Vargas EC, Muñoz-Mejía OA, Zamudio-Burbano MA, Gómez-Corrales JD, Builes-Barrera CA, Román-González A. Cetoacidosis diabética: características epidemiológicas y letalidad en adultos atendidos en un hospital universitario en Colombia. Iatreia. 2021;34-(1):7-14. doi: 10.17533/udea.iatreia.63.
Peters, AL, Buschur EO, Buse JB, Cohan P, Diner J, Hirsch IB. Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium–glucose cotransporter 2 inhibition. Diabetes Care. September 2015; 38:1687–1693. doi: 10.2337/dc15-0843.
Pasquel F, Umpierrez G. Hyperosmolar hyperglycemic state: a historic review of the clinical presentation, diagnosis, and treatment. Diabetes Care. 2014;37(11): 3124–3131. doi: 10.2337/dc14-0984.
Aguirre Espinosa AE, Borja Arias JK, Pozo Arcentales MA, Mendoza Lino BA. Terapéutica de emergencias del síndrome hiperosmolar. RECIMUNDO. 2021; 32, 110-119.
da Rosa LE, Monteiro C, Piccoli Garcia Sh, Grabinski Bottino L, Luchese Custodio J, Heiden Telo G, et al. Precipitating factors of diabetic ketoacidosis in type 1 diabetes patients at a tertiary hospital: a cross-sectional study with a two-time-period comparison. Arch Endocrinol Metab. 202;66(3):335-361. doi: 10.20945/2359-3997000000480.